Plasminogen, the proenzyme of the fibrinolytically active enzyme plasmin, is a single chain glycoprotein with a molecular weight of about 90,000-94,000 Da (2). Various isoelectric forms exist and can be separated by means of isoelectric focusing (IEF).

The complete amino acid sequence contains 790 amino acids. Native plasminogen (glu-plasminogen) has a N-terminal glutamic acid group. Partial plasma proteolysis gives rise to a molecule with N-terminal lysine (lysplasminogen).

Currently, the product has obtained the designation of orphan drug by the US Food and Drug Administration (FDA) and by the European Medicines Agency (EMA). Clinical trials are still underway to obtain Marketing Authorization in the United States and in Europe (EU). The report mainly targeting the research status, predicted competitive landscape, market potential and future trends of plasminogen market.
Plasminogen was originally used as an orphan drug for the treatment of congenital plasminogen deficiency, but the researchers found that he had positive effects on wound care and Diabetic Foot Ulcer treatment. And there is hope that the amputation costs and pain of such patients will be greatly reduced. Once FDA certification is available in the Diabetic Foot Ulcer area, it will benefit significantly from the 10 billion USD amputation market.
China's demand is the biggest and the most direct in the entire potential market. The main reason is that China's gradual growth in per capita consumption and has a relatively good medical system. In addition, China has the largest number of people with diabetes in the world. The market demand is obvious.
If it only acts as an orphan drug, it had almost no development prospects and market, with Congenital Plasminogen Deficiency as an example, the global prevalence around 10 thousand people, we expect 2000-3000 of these people may use the drugs, but the income is far less than the R & D expenditure. But the research team is optimistic about its potential use, especially in wound care and Diabetic Foot Ulcer treatment.

The Global Plasminogen Market touched xxx million USD with a CAGR xx % from 2018-2022 around the world. In the future, it is predicted to reach xxx million USD in 2023 with a CAGR xx % from 2023 - 2030.
As the report focuses on global Plasminogen Market, mainly in Europe and Asia Pacific, North America, Middle East and Africa, and South America. This report segmented the Market on the basis of regions, manufacturers, applications, and type.

in addition, this report introduces Market competition situation among the vendors and company profile, besides, Market price analysis and value chain features are covered in this report.

In Market segmentation by manufacturers, the report covers the following companies-

Kedrion
Prometic
Genentech (Roche)
Boehringer Ingelheim
Kyowa Hakko Kirin
Omeros Corporation
In Market segmentation by geographical regions, the report has analyzed the following regions-
North America (USA, Canada and Mexico)
Europe (Germany, France, UK, Russia and Italy)
Asia-Pacific (China, Japan, Korea, India and Southeast Asia)
South America (Brazil, Argentina, Columbia etc.)
Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa)

In Market segmentation by types covers:

Intravenous Injection
Eye Drops
In Market segmentation by applications :

Ligneous Conjunctivitis
Diabetic Foot
Wound Healing
Others

Apart from the drivers, restraints, and opportunities, the report also offers competitive landscape, including various growth strategies adopted by profiled players for establishing significant position in the industry. The segmentation included in the comprehensive report will help respectable manufacturers to set up their processing units in the regions and increase their global presence. This would also benefit the industry and increase the company\'s product portfolio.

The research provides answers to the following key questions:
• What is the estimated growth rate and Market share and size of the Plasminogen Market for the forecast period 2023 - 2030?
• What are the driving forces in the Plasminogen Market for the forecast period 2023 - 2030?
• Who are the prominent Market players and how have they gained a competitive edge over other competitors?
• What are the Market trends influencing the progress of the Plasminogen industry worldwide?
• What are the major challenges and threats restricting the progress of the industry?
• What opportunities does the Market hold for the prominent Market players?
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